Ho pepesehela lik'hemik'hale tse ling tse bolaeang likokoanyana, tse kang lintho tse lelekang menoang, ho amahanngoa le litlamorao tse mpe bophelong, ho latela tlhahlobo ea lintlha tsa phuputso ea mmuso.
Har'a barupeluoa Phuputsong ea Naha ea Bophelo bo Botle le Phepo e Nepahetseng (NHANES), maemo a holimo a ho pepesehela chefo e bolaeang likokoanyana ea malapeng e sebelisoang hangata e ne e amahanngoa le kotsi e eketsehileng ea lefu la pelo le methapo ea mali (karolelano ea kotsi ke 3.00, 95% CI 1.02–8.80) Ngaka Wei Bao le basebetsi-'moho le eena ba tsoang Univesithing ea Iowa e Iowa City ba tlaleha.
Batho ba kotsing e phahameng ka ho fetisisa ea ho pepesehela chefo ena e bolaeang likokoanyana le bona ba bile le kotsi e eketsehileng ea 56% ea lefu ka lebaka la lisosa tsohle ha ba bapisoa le batho ba kotsing e tlase ka ho fetisisa ea ho pepesehela chefo ena e bolaeang likokoanyana (RR 1.56, 95% CI 1.08–2. 26).
Leha ho le jwalo, bangodi ba hlokometse hore dibolaya-dikokwanyana tsa pyrethroid ha di amane le lefu la kankere (RR 0.91, 95% CI 0.31–2.72).
Mehlala e ile ea fetoloa ho latela morabe/morabe, bong, lilemo, BMI, creatinine, lijo, mokhoa oa bophelo le lintlha tsa kahisano.
Likokoana-hloko tsa Pyrethroid li amohetsoe hore li sebelisoe ke US Environmental Protection Agency 'me hangata li sebelisoa ho li-lester tsa menoang, li-head linter, li-shampoo tsa liphoofolo tse ruuoang lapeng le li-spray, le lihlahisoa tse ling tsa taolo ea likokoanyana ka tlung le kantle 'me li nkoa li sireletsehile haholo.
“Le hoja ho hlahisitsoe di-pyrethroids tse fetang 1,000, ho na le dibolaya-dikokwanyana tse ka bang leshome le metso e mmedi feela tse bolayang dikokwanyana ...
Tlhalosong e tsamaeang le eona, Stephen Stellman, Ph.D., MPH, le Jean Mager Stellman, Ph.D., oa Univesithi ea Columbia e New York, ba hlokomela hore li-pyrethroids “ke chefo ea bobeli e sebelisoang haholo lefatšeng, e leng kakaretso ea lik'hilograma tse likete le lidolara tse limilione tse mashome a makholo a Amerika.” Thekiso ea US ka lidolara tsa Amerika.
Ho feta moo, “dibolaya-dikokwanyana tse bolayang dikokonyana tse bolayang dikokonyana tse nang le di-pyrethroid di atile hohle mme ho pepesehela dikokonyana tsena ho ke ke ha qojwa,” ba ngola jwalo. Hase bothata feela bakeng sa basebetsi ba mapolasing: “Ho fafatsa monoang o fofang ho laola kokoana-hloko ya West Nile le mafu a mang a bakwang ke dikokonyana New York le dibakeng tse ding ho itshetlehile haholo ka dikokonyana tse bolayang dikokonyana tse nang le dikokwana-hloko,” Stelmans o hlokomela.
Phuputso e hlahlobile diphetho tsa batho ba baholo ba fetang 2,000 ba nkileng karolo morerong wa NHANES wa 1999-2000 ba ileng ba etswa ditlhahlobo tsa mmele, ba bokella disampole tsa madi, mme ba araba dipotso tsa phuputso. Ho pepesehela pyrethroid ho ile ha lekanngwa ka maemo a moroto a 3-phenoxybenzoic acid, metabolite ya pyrethroid, mme bankakarolo ba ile ba arolwa ka di-tertiles tsa ho pepesehela.
Nakong ea tlhahlobo e tloaelehileng ea lilemo tse 14, barupeluoa ba 246 ba ile ba hlokahala: ba 52 ba ile ba bolaoa ke kankere le ba 41 ba ile ba bolaoa ke lefu la pelo le methapo ea mali.
Ka karolelano, batho ba batšo bao e seng Mahispanic ba ne ba pepesehetse li-pyrethroids ho feta Mahispanic le makhooa ao e seng Mahispanic. Batho ba nang le chelete e tlase, maemo a tlase a thuto, le boleng bo tlaase ba lijo le bona ba ne ba atisa ho ba le tšoaetso e phahameng ka ho fetisisa ea li-pyrethroids.
Stellman le Stellman ba totobalitse "bophelo bo bokhutšoanyane haholo ba halofo" ea li-biomarker tsa pyrethroid, ka karolelano ea lihora tse 5.7 feela.
“Boteng ba maemo a ka bonoang a metabolites ea pyrethroid e felisoang ka potlako ho baahi ba bangata, ba fapaneng ka libaka bo bontša ho pepesehela nako e telele 'me hape bo etsa hore ho be bohlokoa ho khetholla mehloli e itseng ea tikoloho,” ba hlokometse.
Leha ho le jwalo, ba boetse ba hlokometse hore hobane barupeluoa ba thuto ba ne ba le banyenyane haholo ka dilemo (dilemo tse 20 ho isa ho tse 59), ho thata ho hakanya ka botlalo boholo ba kamano le lefu la pelo le methapo ya madi.
Leha ho le jwalo, "mokgwa o sa tlwaelehang wa kotsi e phahameng" o hloka dipatlisiso tse eketsehileng ka dikhemikhale tsena le dikotsi tsa tsona tse ka bang teng bophelong ba setjhaba, ho boletse Stellman le Stellman.
Moeli o mong oa phuputso ena, ho ea ka bangoli, ke tšebeliso ea lisampole tsa moroto oa tšimo ho lekanya metabolites ea pyrethroid, e ka 'nang ea se ke ea bonahatsa liphetoho ha nako e ntse e ea, e leng se lebisang ho khetholloeng hampe ha ho pepesehela chefo e bolaeang likokoanyana ea pyrethroid khafetsa.
Kristen Monaco ke mongoli e moholo ea ikhethang ka litaba tsa endocrinology, mafu a kelello le nephrology. O sebetsa ofising ea New York 'me esale a le k'hamphaning ho tloha ka 2015.
Phuputso ena e tšehelitsoe ke Mekhatlo ea Naha ea Bophelo bo Botle (NIH) ka Setsi sa Lipatlisiso tsa Bophelo bo Botle ba Tikoloho sa Univesithi ea Iowa.
Nako ea poso: Loetse-26-2023