Florfenicolke motsoako oa motsoako oa monofluoro oa thiamphenicol, foromo ea molek'hule ke C12H14Cl2FNO4S, phofo e tšoeu kapa e tšoeu ea kristale, ha e na monko, e qhibiliha hanyenyane metsing le chloroform, e qhibilihang hanyenyane ka glacial acetic acid, e qhibilihang ka Methanol, ethanol. Ke lithibela-mafu tse ncha tse pharalletseng tsa chloramphenicol bakeng sa ts'ebeliso ea bongaka ba liphoofolo, e ileng ea ntlafatsoa ka katleho bofelong ba lilemo tsa bo-1980.
E ile ea rekisoa ka lekhetlo la pele Japane ka 1990. Ka 1993, Norway e ile ea amohela moriana oo hore o alafshoe salmon. Ka 1995, Fora, United Kingdom, Austria, Mexico le Spain li ile tsa amohela moriana ona bakeng sa ho alafa mafu a baktheria a phefumolohang a likhomo. E boetse e amohetsoe ho sebelisoa e le tlatsetso ea lijo bakeng sa likolobe tsa Japane le Mexico ho thibela le ho alafa mafu a baktheria likolobeng, 'me China joale e amohetse moriana ona.
Ke setlhare sa lithibela-mafu, se hlahisang phello e pharaletseng ea bacteriostatic ka ho thibela ts'ebetso ea peptidyltransferase, 'me e na le mefuta e mengata ea li-antibacterial, ho kenyelletsa le tse fapa-fapaneng.Gram-positivele libaktheria tse mpe le mycoplasma. Libaktheria tse nang le kutloelo-bohloko li kenyelletsa likhomo le porcine Haemophilus,Shigella lets'ollo, Salmonella, Escherichia coli, Pneumococcus, Influenza bacillus, Streptococcus, Staphylococcus aureus, Chlamydia, Leptospira, Rickettsia, joalo-joalo. Sehlahisoa sena se ka hasana ka har'a lisele tsa baktheria ka ho qhibiliha ha lipid, haholo-holo ho sebetsa ho 50s bacterial subunit ea rickettsia, transpeptidase, e sitisa kholo ea peptidase, e thibela ho thehoa ha liketane tsa peptide, kahoo e thibela protheine synthesis, ho finyella morero oa Antibacterial. Sehlahisoa sena se kenngoa ka potlako ke tsamaiso ea molomo, se ajoa ka ho pharaletseng, se na le nako e telele ea halofo ea bophelo, khatello ea meriana e phahameng ea mali, le nako e telele ea ho boloka lithethefatsi tsa mali.
Lilemong tsa morao tjena, mapolasi a mangata a manyenyane le a mahareng a likolobe a sebelisitse florfenicol bakeng sa phekolo ho sa tsotellehe boemo ba likolobe, 'me a sebelisa florfenicol e le lithethefatsi tsa boselamose. Ha e le hantle, sena se kotsi haholo. E na le phello e ntle ea phekolo ho mafu a likolobe a bakoang ke likokoana-hloko tsa Gram-positive le tse mpe le mycoplasma, haholo-holo ka mor'a ho kopana ha florfenicol le doxycycline, phello e ea ntlafatsoa, 'me e sebetsa hantle ho phekola ketane ea porcine thoracic swine atrophic rhinitis. Cocci, joalo-joalo li na le phello e ntle ea ho folisa.
Leha ho le joalo, lebaka leo ka lona ho leng kotsi ho sebelisa florfenicol kamehla ke hobane ho na le litla-morao tse ngata tsa florfenicol, 'me tšebeliso ea nako e telele ea florfenicol e kotsi ho feta molemo. Ka mohlala, metsoalle ea likolobe ha ea lokela ho hlokomoloha lintlha tsena.
1. Haeba ho na le mafu a kokoana-hloko a kang pseudorabies swine fever e nang le lesale la tsebe e putsoa polasing ea likolobe, tšebeliso ea florfenicol bakeng sa phekolo hangata e tla fetoha karolo ea mafu ana a kokoana-hloko, kahoo haeba mafu a ka holimo a tšoaelitsoe 'me a e-na le ho latela mafu a mang a likolobe, u se ke ua sebelisa florfenicol bakeng sa phekolo, e tla mpefatsa lefu lena.
2. Florfenicol e tla kena-kenana le tsamaiso ea rona ea mali le ho thibela tlhahiso ea lisele tse khubelu tsa mali mokong oa masapo, haholo-holo haeba likolobe tsa rona tse anyesang li na le sefuba kapa manonyeletso a ruruhileng. Mmala oa moriri oa kolobe ha o shebahale hantle, moriri o halikiloeng, empa hape o bontša matšoao a phokolo ea mali, hape o tla etsa hore kolobe e se ke ea ja nako e telele, ho etsa kolobe e thata.
3. Florfenicol ke embryotoxic. Haeba florfenicol e atisa ho sebelisoa nakong ea bokhachane ho tse tšehali, likolobe tse hlahisoang li tla hlōleha.
4. Tšebeliso ea nako e telele ea florfenicol e tla baka mathata a mala le letšollo likolobe.
5. Ho bonolo ho baka tšoaetso ea bobeli, e kang dermatitis ea exudative e bakoang ke tšoaetso ea staphylococcus likolobe kapa tšoaetso ea bobeli ea dermatitis e meng ea fungal.
Ho akaretsa, florfenicol ha ea lokela ho sebelisoa e le sethethefatsi se tloaelehileng. Ha re sebelisa lithibela-mafu tse ling tse nang le phello e mpe 'me li le ka kutloisiso e tsoakaneng (ho leleka kokoana-hloko), re ka sebelisa florfenicol le doxycycline ka lehlakoreng. Acupuncture e sebelisoa ho phekola maloetse a sa khoneng ho phekoloa, 'me ha e khothalletsoe bakeng sa maemo a mang.
Nako ea poso: Jul-14-2022