Florfenicolke motsoako oa motsoako oa monofluoro oa thiamphenicol, foromo ea molek'hule ke C12H14Cl2FNO4S, phofo e tšoeu kapa e tšoeu ea kristale, ha e na monko, e qhibiliha hanyenyane metsing le chloroform, e qhibilihang hanyenyane ka glacial acetic acid, e qhibilihang ka Methanol, ethanol.Ke lithibela-mafu tse ncha tse pharalletseng tsa chloramphenicol bakeng sa ts'ebeliso ea bongaka ba liphoofolo, e ileng ea ntlafatsoa ka katleho bofelong ba lilemo tsa bo-1980.
E ile ea rekisoa ka lekhetlo la pele Japane ka 1990. Ka 1993, Norway e ile ea amohela moriana oo hore o alafshoe salmon.Ka 1995, Fora, United Kingdom, Austria, Mexico le Spain li ile tsa amohela moriana ona bakeng sa ho alafa mafu a baktheria a phefumolohang a likhomo.E boetse e amohetsoe ho sebelisoa e le tlatsetso ea lijo bakeng sa likolobe tsa Japane le Mexico ho thibela le ho alafa mafu a baktheria likolobeng, 'me China joale e amohetse moriana ona.
Ke setlhare sa lithibela-mafu, se hlahisang phello e pharaletseng ea bacteriostatic ka ho thibela ts'ebetso ea peptidyltransferase, 'me e na le mefuta e mengata ea li-antibacterial, ho kenyelletsa le tse fapa-fapaneng.Gram-positivele libaktheria tse mpe le mycoplasma.Libaktheria tse nang le kutloelo-bohloko li kenyelletsa likhomo le porcine Haemophilus,Shigella lets'ollo, Salmonella, Escherichia coli, Pneumococcus, Influenza bacillus, Streptococcus, Staphylococcus aureus, Chlamydia, Leptospira, Rickettsia, joalo-joalo. Sehlahisoa sena se ka kena liseleng tsa baktheria ka ho qhibiliha ha lipid, haholo-holo se sebetsa ho 50s bacterial transsomenders, kholo ea peptidase, e thibela ho thehoa ha liketane tsa peptide, ka hona ho thibela protheine synthesis, ho finyella morero oa Antibacterial.Sehlahisoa sena se kenngoa ka potlako ke tsamaiso ea molomo, se ajoa ka ho pharaletseng, se na le nako e telele ea halofo ea bophelo, khatello ea meriana e phahameng ea mali, le nako e telele ea ho boloka lithethefatsi tsa mali.
Lilemong tsa morao tjena, mapolasi a mangata a manyenyane le a mahareng a likolobe a sebelisitse florfenicol bakeng sa phekolo ho sa tsotellehe boemo ba likolobe, 'me a sebelisa florfenicol e le lithethefatsi tsa boselamose.Ha e le hantle, sena se kotsi haholo.E na le phello e ntle ea phekolo ho mafu a likolobe a bakoang ke likokoana-hloko tsa Gram-positive le tse mpe le mycoplasma, haholo-holo ka mor'a ho kopana ha florfenicol le doxycycline, phello e ea ntlafatsoa, 'me e sebetsa hantle ho phekola ketane ea porcine thoracic swine atrophic rhinitis.Cocci, joalo-joalo li na le phello e ntle ea ho folisa.
Leha ho le joalo, lebaka leo ka lona ho leng kotsi ho sebelisa florfenicol kamehla ke hobane ho na le litla-morao tse ngata tsa florfenicol, 'me tšebeliso ea nako e telele ea florfenicol e kotsi ho feta molemo.Ka mohlala, metsoalle ea likolobe ha ea lokela ho hlokomoloha lintlha tsena.
1. Haeba ho na le mafu a kokoana-hloko a kang pseudorabies swine fever e nang le lesale la tsebe e putsoa polasing ea likolobe, tšebeliso ea florfenicol bakeng sa phekolo hangata e tla fetoha karolo ea mafu ana a kokoana-hloko, kahoo haeba mafu a ka holimo a tšoaelitsoe 'me a e-na le ho latela mafu a mang a likolobe, u se ke ua sebelisa florfenicol bakeng sa phekolo, e tla mpefatsa lefu lena.
2. Florfenicol e tla kena-kenana le tsamaiso ea rona ea mali le ho thibela tlhahiso ea lisele tse khubelu tsa mali mokong oa masapo, haholo-holo haeba likolobe tsa rona tse anyesang li na le sefuba kapa manonyeletso a ruruhileng.Mmala oa moriri oa kolobe ha o shebahale hantle, moriri o halikiloeng, empa hape o bontša matšoao a phokolo ea mali, hape o tla etsa hore kolobe e se ke ea ja nako e telele, ho etsa kolobe e thata.
3. Florfenicol ke embryotoxic.Haeba florfenicol e atisa ho sebelisoa nakong ea bokhachane ho tse tšehali, likolobe tse hlahisoang li tla hlōleha.
4. Tšebeliso ea nako e telele ea florfenicol e tla baka mathata a mala le letšollo likolobe.
5. Ho bonolo ho baka tšoaetso ea bobeli, e kang dermatitis ea exudative e bakoang ke tšoaetso ea staphylococcus likolobe kapa tšoaetso ea bobeli ea dermatitis e meng ea fungal.
Ho akaretsa, florfenicol ha ea lokela ho sebelisoa e le sethethefatsi se tloaelehileng.Ha re sebelisa lithibela-mafu tse ling tse nang le phello e mpe 'me li le ka kutloisiso e tsoakaneng (ho leleka kokoana-hloko), re ka sebelisa florfenicol le doxycycline ka lehlakoreng.Acupuncture e sebelisoa ho phekola maloetse a sa khoneng ho phekoloa, 'me ha e khothalletsoe bakeng sa maemo a mang.
Nako ea poso: Jul-14-2022